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Molecular Pharmacology, Vol 2, 56-66, Copyright © 1966 by the American Society for Pharmacology and Experimental Therapeutics

The Sulfotransferases of Guinea Pig Liver

R. K. BANERJEE 1 and A. B. ROY 1

1 Department of Physical Biochemistry, Australian National University, Canberra, Australia

A method is described for the separation of the sulfotransferases of guinea pig liver. A phenol sulfotransferase has been obtained free from any other sulfurylating activity so far sought. Androstenolone sulfotransferase and estrone sulfotransferase have been partially separated, and it is suggested that both these enzymes also sulfurylate p-nitrophenol and 2-naphthylamine. Deoxycorticosterone sulfate is almost certainly formed by another sulfotransferase.

Submitted on October 29, 1965






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