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Molecular Pharmacology, Vol 2, 606-608, Copyright © 1966 by the American Society for Pharmacology and Experimental Therapeutics

The Effect of Reserpine on Growth and Catecholamine Content of Tetrahymena

J. J. BLUM 1, N. KIRSHNER 1, and J. UTLEY 1

1 Departments of Physiology, Biochemistry, and Pharmacology, Duke University School of Medicine, Durham, North Carolina 27706

Reserpine inhibits the growth of Tetrahymena and reduces the content of epinephrine and of norepinephrine of these cells. The growth inhibitory effect is partially reversed by glucose.

Note:
This work was supported by grants from the National Science Foundation (GB 2788), the National Institutes of Health (5 RO1 HD 01269 and AM 05427). Drs. Blum and Kirshner also acknowledge the support of Research Career Development Awards (K3-GM-2341 and K3-GM-15184) from the National Institutes of Health.

Submitted on August 22, 1966






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