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March 1998; 53 (3)   [Index by Author]  [Cover Caption]
       Accelerated Communication
       Articles
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Accelerated Communication:

Sankar Mitra, Mehmet Ugur, Ozlem Ugur, H. Maurice Goodman, John R. McCullough, and Hiroshi Yamaguchi
(S)-Albuterol Increases Intracellular Free Calcium by Muscarinic Receptor Activation and a Phospholipase C-Dependent Mechanism in Airway Smooth Muscle
Mol Pharmacol 1998 53: 347-354. [Abstract] [Full Text] [PDF]  

Articles:

Brian D. Schlag, Joanna R. Vondrasek, Muhammad Munir, Avtandil Kalandadze, Olga A. Zelenaia, Jeffrey D. Rothstein, and Michael B. Robinson
Regulation of the Glial Na+-Dependent Glutamate Transporters by Cyclic AMP Analogs and Neurons
Mol Pharmacol 1998 53: 355-369. [Abstract] [Full Text] [PDF]  

Anne Marjamäki, Marjo Pihlavisto, Victor Cockcroft, Petri Heinonen, Juha-Matti Savola, and Mika Scheinin
Chloroethylclonidine Binds Irreversibly to Exposed Cysteines in the Fifth Membrane-Spanning Domain of the Human alpha 2A-Adrenergic Receptor
Mol Pharmacol 1998 53: 370-376. [Abstract] [Full Text] [PDF]  

Duane E. Keith, Benito Anton, Stephen R. Murray, Paulette A. Zaki, Peter C. Chu, Dmitri V. Lissin, Ghislaine Monteillet-Agius, Phoebe L. Stewart, Christopher J. Evans, and Mark von Zastrow
µ-Opioid Receptor Internalization: Opiate Drugs Have Differential Effects on a Conserved Endocytic Mechanism In Vitro and in the Mammalian Brain
Mol Pharmacol 1998 53: 377-384. [Abstract] [Full Text] [PDF]  

Thomas Klein, Volker Ullrich, Josef Pfeilschifter, and Rolf Nüsing
On the Induction of Cyclooxygenase-2, Inducible Nitric Oxide Synthase and Soluble Phospholipase A2 in Rat Mesangial Cells by a Nonsteroidal Anti-Inflammatory Drug: The Role of Cyclic AMP
Mol Pharmacol 1998 53: 385-391. [Abstract] [Full Text] [PDF]  

William G. Conroy and Darwin K. Berg
Nicotinic Receptor Subtypes in the Developing Chick Brain: Appearance of a Species Containing the alpha 4, beta 2, and alpha 5 Gene Products
Mol Pharmacol 1998 53: 392-401. [Abstract] [Full Text] [PDF]  

Verena M. Dirsch, Alexander L. Gerbes, and Angelika M. Vollmar
Ajoene, a Compound of Garlic, Induces Apoptosis in Human Promyeloleukemic Cells, Accompanied by Generation of Reactive Oxygen Species and Activation of Nuclear Factor kappa B
Mol Pharmacol 1998 53: 402-407. [Abstract] [Full Text] [PDF]  

Jacqueline Loeper, Annie Le Berre, and Denis Pompon
Topology Inversion of CYP2D6 in the Endoplasmic Reticulum Is Not Required for Plasma Membrane Transport
Mol Pharmacol 1998 53: 408-414. [Abstract] [Full Text] [PDF]  

Lalitha Ramamoorthy and Ian R. Tizard
Induction of Apoptosis in a Macrophage Cell Line RAW 264.7 By Acemannan, a beta -(1,4)-Acetylated Mannan
Mol Pharmacol 1998 53: 415-421. [Abstract] [Full Text] [PDF]  

Tsvetan G. Gantchev and Darel J. Hunting
The Ortho-Quinone Metabolite of the Anticancer Drug Etoposide (VP-16) Is a Potent Inhibitor of the Topoisomerase II/DNA Cleavable Complex
Mol Pharmacol 1998 53: 422-428. [Abstract] [Full Text] [PDF]  

Anthone W. Dunah, Jianhong Luo, Yue-Hua Wang, Robert P. Yasuda, and Barry B. Wolfe
Subunit Composition of N-Methyl-D-aspartate Receptors in the Central Nervous System that Contain the NR2D Subunit
Mol Pharmacol 1998 53: 429-437. [Abstract] [Full Text] [PDF]  

John J. Reiners Jr., Jing-Yu Lee, Russell E. Clift, David T. Dudley, and Scott P. Myrand
PD98059 Is an Equipotent Antagonist of the Aryl Hydrocarbon Receptor and Inhibitor of Mitogen-Activated Protein Kinase Kinase
Mol Pharmacol 1998 53: 438-445. [Abstract] [Full Text] [PDF]  

Christopher W. Benjamin, Ronald R. Hiebsch, and David A. Jones
Caspase Activation in MCF7 Cells Responding to Etoposide Treatment
Mol Pharmacol 1998 53: 446-450. [Abstract] [Full Text] [PDF]  

Steve A. Carlson, Tapan K. Chatterjee, Kenneth P. Murphy, and Rory A. Fisher
Mutation of a Putative Amphipathic alpha -Helix in the Third Intracellular Domain of the Platelet-Activating Factor Receptor Disrupts Receptor/G Protein Coupling and Signaling
Mol Pharmacol 1998 53: 451-458. [Abstract] [Full Text] [PDF]  

Yong-Tai Hou, Hsueh-Kung Lin, and Trevor M. Penning
Dexamethasone Regulation of the Rat 3alpha -Hydroxysteroid/Dihydrodiol Dehydrogenase Gene
Mol Pharmacol 1998 53: 459-466. [Abstract] [Full Text] [PDF]  

Jih-Hwa Guh, Tsong-Long Hwang, Feng-Nien Ko, Shih-Chieh Chueh, Ming-Kuen Lai, and Che-Ming Teng
Antiproliferative Effect in Human Prostatic Smooth Muscle Cells by Nitric Oxide Donor
Mol Pharmacol 1998 53: 467-474. [Abstract] [Full Text] [PDF]  

Heike Hellmold, Malin Magnusson, Markku Pelto-Huikko, Tove Rylander, Jan-Åke Gustafsson, and Margaret Warner
Identification of CYP2A3 as a Major Cytochrome P450 Enzyme in the Female Peripubertal Rat Breast
Mol Pharmacol 1998 53: 475-482. [Abstract] [Full Text] [PDF]  

Stephan Immenschuh, Thomas Kietzmann, Vera Hinke, Matthias Wiederhold, Norbert Katz, and Ursula Muller-Eberhard
The Rat Heme Oxygenase-1 Gene Is Transcriptionally Induced via the Protein Kinase A Signaling Pathway in Rat Hepatocyte Cultures
Mol Pharmacol 1998 53: 483-491. [Abstract] [Full Text] [PDF]  

Phantip Vattanaviboon, Prapon Wilairat, and Yongyuth Yuthavong
Binding of Dihydroartemisinin to Hemoglobin H: Role in Drug Accumulation and Host-Induced Antimalarial Ineffectiveness of alpha -Thalassemic Erythrocytes
Mol Pharmacol 1998 53: 492-496. [Abstract] [Full Text] [PDF]  

Midori Kawakami and Eiichiro Okabe
Superoxide Anion Radical-Triggered Ca2+ Release from Cardiac Sarcoplasmic Reticulum through Ryanodine Receptor Ca2+ Channel
Mol Pharmacol 1998 53: 497-503. [Abstract] [Full Text] [PDF]  

Allyn C. Howlett, Chao Song, Barbara A. Berglund, Gerald H. Wilken, and J. Jill Pigg
Characterization of CB1 Cannabinoid Receptors Using Receptor Peptide Fragments and Site-Directed Antibodies
Mol Pharmacol 1998 53: 504-510. [Abstract] [Full Text] [PDF]  

Yongchang Chang and David S. Weiss
Substitutions of the Highly Conserved M2 Leucine Create Spontaneously Opening rho 1 gamma -Aminobutyric Acid Receptors
Mol Pharmacol 1998 53: 511-523. [Abstract] [Full Text] [PDF]  

Ming-Ming Zhao, Robert J. Gaivin, and Dianne M. Perez
The Third Extracellular Loop of the beta 2-Adrenergic Receptor Can Modulate Receptor/G Protein Affinity
Mol Pharmacol 1998 53: 524-529. [Abstract] [Full Text] [PDF]  

Matthew D. Krasowski, Vladimir V. Koltchine, Caroline E. Rick, Qing Ye, Suzanne E. Finn, and Neil L. Harrison
Propofol and Other Intravenous Anesthetics Have Sites of Action on the gamma -Aminobutyric Acid Type A Receptor Distinct from That for Isoflurane
Mol Pharmacol 1998 53: 530-538. [Abstract] [Full Text] [PDF]  

Kenneth B. Walsh and Chongmin Wang
Arylaminobenzoate Block of the Cardiac Cyclic AMP-Dependent Chloride Current
Mol Pharmacol 1998 53: 539-546. [Abstract] [Full Text] [PDF]  

Georg Kojda, Markus Patzner, Andreas Hacker, and Eike Noack
Nitric Oxide Inhibits Vascular Bioactivation of Glyceryl Trinitrate: A Novel Mechanism to Explain Preferential Venodilation of Organic Nitrates
Mol Pharmacol 1998 53: 547-554. [Abstract] [Full Text] [PDF]  

Bruno Buisson and Daniel Bertrand
Open-Channel Blockers at the Human alpha 4beta 2 Neuronal Nicotinic Acetylcholine Receptor
Mol Pharmacol 1998 53: 555-563. [Abstract] [Full Text] [PDF]  

Quan Chen, John W. Olney, Peter D. Lukasiewicz, Todd Almli, and Carmelo Romano
Ca2+-Independent Excitotoxic Neurodegeneration in Isolated Retina, an Intact Neural Net: A Role for Cl- and Inhibitory Transmitters
Mol Pharmacol 1998 53: 564-572. [Abstract] [Full Text] [PDF]  

S. Lazareno, P. Gharagozloo, D. Kuonen, A. Popham, and N. J. M. Birdsall
Subtype-Selective Positive Cooperative Interactions between Brucine Analogues and Acetylcholine at Muscarinic Receptors: Radioligand Binding Studies
Mol Pharmacol 1998 53: 573-589. [Abstract] [Full Text] [PDF]  

Philip Wahl, Charlotte Anker, Stephen F. Traynelis, Jan Egebjerg, Jesper S. Rasmussen, Povl Krogsgaard-Larsen, and Ulf Madsen
Antagonist Properties of a Phosphono Isoxazole Amino Acid at Glutamate R1-4 (R,S)-2-Amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionic Acid Receptor Subtypes
Mol Pharmacol 1998 53: 590-596. [Abstract] [Full Text] [PDF]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.


Cover Caption:

About the cover: Hypothetical structure of amphotericin B channel in aqueous solution. Left, view from extracellular surface. Green, carbon atoms; red, oxygen atoms; blue, nitrogen atoms; white, hydrogen atoms. Cholesterol molecules are shown in magenta. Right, view from within the membrane as a side projection. The amphotericin B molecule is shown in green, cholesterol in magenta. Water molecules included in the simulation are shown above and below the channel. From Baginski M, Resat H, and McCammon JA (1997) Molecular properties of Amphotericin B membrane channel: A molecular dynamics simulation. Mol. Pharmacol. 52:560-570



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