Accelerated Communications:

Anders J. Bolmstedt, Barry R. O'Keefe, Shilpa R. Shenoy, James B. McMahon, and Michael R. Boyd

Cyanovirin-N Defines a New Class of Antiviral Agent Targeting N-Linked, High-Mannose Glycans in an Oligosaccharide-Specific Manner
Mol Pharmacol 2001 59: 949-954. [Abstract] [Full Text] [PDF]  

Cristina Sánchez, Daniel Rueda, Bruno Ségui, Ismael Galve-Roperh, Thierry Levade, and Manuel Guzmán

The CB₁ Cannabinoid Receptor of Astrocytes Is Coupled to Sphingomyelin Hydrolysis through the Adaptor Protein Fan
Mol Pharmacol 2001 59: 955-959. [Abstract] [Full Text] [PDF]  

Guey-Ying Liao, David A. Wagner, Michael H. Hsu, and John P. Leonard

Evidence for Direct Protein Kinase-C Mediated Modulation of N-Methyl-D-aspartate Receptor Current
Mol Pharmacol 2001 59: 960-964. [Abstract] [Full Text] [PDF]  

Fiona Y. Carroll, Andreas Stolle, Philip M. Beart, Arnd Voerste, Isabelle Brabet, Frank Mauler, Cécile Joly, Horst Antonicek, Joël Bockaert, Thomas Müller, Jean Philippe Pin, and Laurent Prézeau

BAY36-7620: A Potent Non-Competitive mGlu1 Receptor Antagonist with Inverse Agonist Activity.
Mol Pharmacol 2001 59: 965-973. [Abstract] [Full Text] [PDF]  

Articles:

Christoph G. Dietrich, D. Rudi de Waart, Roel Ottenhoff, Ivo G. Schoots, and Ronald P. J. Oude Elferink

Increased Bioavailability of the Food-Derived Carcinogen 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in MRP2-Deficient Rats
Mol Pharmacol 2001 59: 974-980. [Abstract] [Full Text] [PDF]  

Soo-Jung Eom, Eun Young Kim, Ji Eun Lee, Hyo Jung Kang, Jaekyung Shim, Seong Up Kim, Byoung Joo Gwag, and Eui-Ju Choi

Zn²⁺ Induces Stimulation of the c-Jun N-Terminal Kinase Signaling Pathway through Phosphoinositide 3-Kinase
Mol Pharmacol 2001 59: 981-986. [Abstract] [Full Text] [PDF]  

Huan-Chen Li, Dongxu Liu, and David J. Waxman

Transcriptional Induction of Hepatic NADPH: Cytochrome P450 Oxidoreductase by Thyroid Hormone
Mol Pharmacol 2001 59: 987-995. [Abstract] [Full Text] [PDF]  

Graham Rena, Fiona Begg, Annette Ross, Carolynn MacKenzie, Ian McPhee, Lachlan Campbell, Elaine Huston, Michael Sullivan, and Miles D. Houslay

Molecular Cloning, Genomic Positioning, Promoter Identification, and Characterization of the Novel Cyclic AMP-Specific Phosphodiesterase PDE4A10
Mol Pharmacol 2001 59: 996-1011. [Abstract] [Full Text] [PDF]  

A. C. Megson, E. M. Walker, and S. J. Hill

Role of Protein Kinase C in Signaling from the Histamine H₁ Receptor to the Nucleus
Mol Pharmacol 2001 59: 1012-1021. [Abstract] [Full Text] [PDF]  

Iraida G. Sharina, Rongbao Zhao, Yanhua Wang, Solomon Babani, and I. David Goldman

Mutational Analysis of the Functional Role of Conserved Arginine and Lysine Residues in Transmembrane Domains of the Murine Reduced Folate Carrier
Mol Pharmacol 2001 59: 1022-1028. [Abstract] [Full Text] [PDF]  

Huizhen Wang, Hong Han, Liming Zhang, Hong Shi, Gernot Schram, Stanley Nattel, and Zhiguo Wang

Expression of Multiple Subtypes of Muscarinic Receptors and Cellular Distribution in the Human Heart
Mol Pharmacol 2001 59: 1029-1036. [Abstract] [Full Text] [PDF]  

Darrel J. Pemberton, Christopher J. Franks, Robert J. Walker, and Lindy Holden-Dye

Characterization of Glutamate-Gated Chloride Channels in the Pharynx of Wild-Type and Mutant Caenorhabditis elegans Delineates the Role of the Subunit GluCl-2 in the Function of the Native Receptor
Mol Pharmacol 2001 59: 1037-1043. [Abstract] [Full Text] [PDF]  

Michael T. Osinski, Bernhard H. Rauch, and Karsten Schrör

Antimitogenic Actions of Organic Nitrates Are Potentiated by Sildenafil and Mediated Via Activation of Protein Kinase A
Mol Pharmacol 2001 59: 1044-1050. [Abstract] [Full Text] [PDF]  

Hugo R. Arias, Elizabeth A. McCardy, and Michael P. Blanton

Characterization of the Dizocilpine Binding Site on the Nicotinic Acetylcholine Receptor
Mol Pharmacol 2001 59: 1051-1060. [Abstract] [Full Text] [PDF]  

Yi Liu, Dong Liu, Louise Heath, Diane M. Meyers, Douglas S. Krafte, P. Kay Wagoner, Christopher P. Silvia, Weifeng Yu, and Mark E. Curran

Direct Activation of an Inwardly Rectifying Potassium Channel by Arachidonic Acid
Mol Pharmacol 2001 59: 1061-1068. [Abstract] [Full Text] [PDF]  

Shetuan Zhang, Sridharan Rajamani, Yuenmu Chen, Qiuming Gong, Yajing Rong, Zhengfeng Zhou, Arnold Ruoho, and Craig T. January

Cocaine Blocks HERG, but Not KvLQT1+minK, Potassium Channels
Mol Pharmacol 2001 59: 1069-1076. [Abstract] [Full Text] [PDF]  

Kousei Ito, Hiroshi Suzuki, and Yuichi Sugiyama

Charged Amino Acids in the Transmembrane Domains Are Involved in the Determination of the Substrate Specificity of Rat Mrp2
Mol Pharmacol 2001 59: 1077-1085. [Abstract] [Full Text] [PDF]  

Tobias Krauter, J. Peter Ruppersberg, and Thomas Baukrowitz

Phospholipids as Modulators of K_ATP Channels: Distinct Mechanisms for Control of Sensitivity to Sulphonylureas, K⁺ Channel Openers, and ATP
Mol Pharmacol 2001 59: 1086-1093. [Abstract] [Full Text] [PDF]  

Yasumasa Ito, Pramod Pandey, Michael B. Sporn, Rakesh Datta, Surender Kharbanda, and Donald Kufe

The Novel Triterpenoid CDDO Induces Apoptosis and Differentiation of Human Osteosarcoma Cells by a Caspase-8 Dependent Mechanism
Mol Pharmacol 2001 59: 1094-1099. [Abstract] [Full Text] [PDF]  

Sho-Ya Wang, Maria Barile, and Ging Kuo Wang

Disparate Role of Na⁺ Channel D2-S6 Residues in Batrachotoxin and Local Anesthetic Action
Mol Pharmacol 2001 59: 1100-1107. [Abstract] [Full Text] [PDF]  

Alison J. Smith, Luanda Alder, Jonathan Silk, Charles Adkins, Alan E. Fletcher, Tim Scales, Julie Kerby, George Marshall, Keith A. Wafford, Ruth M. McKernan, and John R. Atack

Effect of Subunit on Allosteric Modulation of Ion Channel Function in Stably Expressed Human Recombinant -Aminobutyric Acid_A Receptors Determined Using ³⁶Cl Ion Flux
Mol Pharmacol 2001 59: 1108-1118. [Abstract] [Full Text] [PDF]  

Forbes Alderton, Patrick P. A. Humphrey, and Lynda A. Sellers

High-Intensity p38 Kinase Activity Is Critical for p21^cip1 Induction and the Antiproliferative Function of G_i Protein-Coupled Receptors
Mol Pharmacol 2001 59: 1119-1128. [Abstract] [Full Text] [PDF]  

Harald H. Sitte, Birgit Hiptmair, Julia Zwach, Christian Pifl, Ernst A. Singer, and Petra Scholze

Quantitative Analysis of Inward and Outward Transport Rates in Cells Stably Expressing the Cloned Human Serotonin Transporter: Inconsistencies with the Hypothesis of Facilitated Exchange Diffusion
Mol Pharmacol 2001 59: 1129-1137. [Abstract] [Full Text] [PDF]  

Jaspreet S. Sidhu, Fei Liu, Sean M. Boyle, and Curtis J. Omiecinski

PI3K Inhibitors Reverse the Suppressive Actions of Insulin on CYP2E1 Expression by Activating Stress-Response Pathways in Primary Rat Hepatocytes
Mol Pharmacol 2001 59: 1138-1146. [Abstract] [Full Text] [PDF]  

Keon Wook Kang, Min Kyung Cho, Chang Ho Lee, and Sang Geon Kim

Activation of Phosphatidylinositol 3-Kinase and Akt by tert-Butylhydroquinone Is Responsible for Antioxidant Response Element-Mediated rGSTA2 Induction in H4IIE Cells
Mol Pharmacol 2001 59: 1147-1156. [Abstract] [Full Text] [PDF]  

Roxanne A. Vaughan, Jon D. Gaffaney, John R. Lever, Maarten E. A. Reith, and Aloke K. Dutta

Dual Incorporation of Photoaffinity Ligands on Dopamine Transporters Implicates Proximity of Labeled Domains
Mol Pharmacol 2001 59: 1157-1164. [Abstract] [Full Text] [PDF]  

V. Bourgarel-Rey, S. Vallee, O. Rimet, S. Champion, D. Braguer, A. Desobry, C. Briand, and Y. Barra

Involvement of Nuclear Factor B in c-Myc Induction by Tubulin Polymerization Inhibitors
Mol Pharmacol 2001 59: 1165-1170. [Abstract] [Full Text] [PDF]  

Elaine M. Leslie, Qingcheng Mao, Curtis J. Oleschuk, Roger G. Deeley, and Susan P. C. Cole

Modulation of Multidrug Resistance Protein 1 (MRP1/ABCC1) Transport and ATPase Activities by Interaction with Dietary Flavonoids
Mol Pharmacol 2001 59: 1171-1180. [Abstract] [Full Text] [PDF]  

An R. Van Rompay, Ameli Norda, Karin Lindén, Magnus Johansson, and Anna Karlsson

Phosphorylation of Uridine and Cytidine Nucleoside Analogs by Two Human Uridine-Cytidine Kinases
Mol Pharmacol 2001 59: 1181-1186. [Abstract] [Full Text] [PDF]  

Eric S. Dawson and Jack N. Wells

Determination of Amino Acid Residues that are Accessible from the Ligand Binding Crevice in the Seventh Transmembrane-Spanning Region of the Human A₁ Adenosine Receptor
Mol Pharmacol 2001 59: 1187-1195. [Abstract] [Full Text] [PDF]  

Judith Sylvester, Abdelhamid Liacini, Wen Qing Li, Faramaze Dehnade, and Muhammad Zafarullah

Tripterygium wilfordii Hook F Extract Suppresses Proinflammatory Cytokine-Induced Expression of Matrix Metalloproteinase Genes in Articular Chondrocytes by Inhibiting Activating Protein-1 and Nuclear Factor-B Activities
Mol Pharmacol 2001 59: 1196-1205. [Abstract] [Full Text] [PDF]  

Vanessa Correa, Andrew M. Riley, Satoshi Shuto, Graeme Horne, Edmund P. Nerou, Rachel D. Marwood, Barry V. L. Potter, and Colin W. Taylor

Structural Determinants of Adenophostin A Activity at Inositol Trisphosphate Receptors
Mol Pharmacol 2001 59: 1206-1215. [Abstract] [Full Text] [PDF]  

Eunseon Hur, Keun Young Chang, Eunjung Lee, Seung-Ki Lee, and Hyunsung Park

Mitogen-Activated Protein Kinase Kinase Inhibitor PD98059 Blocks the trans-Activation but Not the Stabilization or DNA Binding Ability of Hypoxia-Inducible Factor-1
Mol Pharmacol 2001 59: 1216-1224. [Abstract] [Full Text] [PDF]  

Timothy D. O'Connell, D. Gregg Rokosh, and Paul C. Simpson

Cloning and Characterization of the Mouse 1C/A-Adrenergic Receptor Gene and Analysis of an 1C Promoter in Cardiac Myocytes: Role of an MCAT Element That Binds Transcriptional Enhancer Factor-1 (TEF-1)
Mol Pharmacol 2001 59: 1225-1234. [Abstract] [Full Text] [PDF]  

E. Ducza, R. Gáspár, A. Márki, P. Gyula, S. Bottka, and G. Falkay

Use of Antisense Oligonucleotides to Verify the Role of the _1A-Adrenergic Receptor in the Contractility of the Rat Uterus Post Partum
Mol Pharmacol 2001 59: 1235-1242. [Abstract] [Full Text] [PDF]  

Elsé Marais, Norbert Klugbauer, and Franz Hofmann

Calcium Channel ₂ SubunitsStructure and Gabapentin Binding
Mol Pharmacol 2001 59: 1243-1248. [Abstract] [Full Text] [PDF]  

Onyou Hwang, Guncheol Kim, Yeon Joo Jang, Seong Who Kim, Guiyong Choi, Hyun Jin Choi, Seon Young Jeon, Don Gyu Lee, and Jae Dam Lee

Synthetic Phytoceramides Induce Apoptosis with Higher Potency than Ceramides
Mol Pharmacol 2001 59: 1249-1255. [Abstract] [Full Text] [PDF]  

Aaron G. Roseberry, Moritz Bünemann, Jyoti Elavunkal, and M. Marlene Hosey

Agonist-Dependent Delivery of M₂ Muscarinic Acetylcholine Receptors to the Cell Surface after Pertussis Toxin Treatment
Mol Pharmacol 2001 59: 1256-1268. [Abstract] [Full Text] [PDF]  

Uwe Werling, Sandra Siehler, Margarethe Litfin, Heinz Nau, and Martin Göttlicher

Induction of Differentiation in F9 Cells and Activation of Peroxisome Proliferator-Activated Receptor by Valproic Acid and Its Teratogenic Derivatives
Mol Pharmacol 2001 59: 1269-1276. [Abstract] [Full Text] [PDF]  

Seok Ho Cha, Takashi Sekine, Jun-ichi Fukushima, Yoshikatsu Kanai, Yukari Kobayashi, Tomoyuki Goya, and Hitoshi Endou

Identification and Characterization of Human Organic Anion Transporter 3 Expressing Predominantly in the Kidney
Mol Pharmacol 2001 59: 1277-1286. [Abstract] [Full Text] [PDF]  

Yutaro Obara, Hironori Kobayashi, Tomihisa Ohta, Yasushi Ohizumi, and Norimichi Nakahata

Scabronine G-Methylester Enhances Secretion of Neurotrophic Factors Mediated by an Activation of Protein Kinase C-
Mol Pharmacol 2001 59: 1287-1297. [Abstract] [Full Text] [PDF]  

Andrew M. W. Stead, Patrick G. Bray, I. Geoffrey Edwards, Harry P. DeKoning, Barry C. Elford, Paul A. Stocks, and Stephen A. Ward

Diamidine Compounds: Selective Uptake and Targeting in Plasmodium falciparum
Mol Pharmacol 2001 59: 1298-1306. [Abstract] [Full Text] [PDF]  

Philippe Nirdé, Béatrice Térouanne, Nadine Gallais, Charles Sultan, and Gilles Auzou

Antimineralocorticoid 11-Substituted Spirolactones Exhibit Androgen Receptor Agonistic Activity: A Structure Function Study
Mol Pharmacol 2001 59: 1307-1313. [Abstract] [Full Text] [PDF]  

Silvia Ginés, Franciso Ciruela, Javier Burgueño, Vicent Casadó, Enric. I. Canela, Josefa Mallol, Carme Lluís, and Rafael Franco

Involvement of Caveolin in Ligand-Induced Recruitment and Internalization of A₁ Adenosine Receptor and Adenosine Deaminase in an Epithelial Cell Line
Mol Pharmacol 2001 59: 1314-1323. [Abstract] [Full Text] [PDF]  

Vaishali Hadkar and Randal A. Skidgel

Carboxypeptidase D Is Up-Regulated in RAW 264.7 Macrophages and Stimulates Nitric Oxide Synthesis by Cells in Arginine-Free Medium
Mol Pharmacol 2001 59: 1324-1332. [Abstract] [Full Text] [PDF]  

Chia-Hsin Yeh, Hui-Chin Peng, Rong-Seng Yang, and Tur-Fu Huang

Rhodostomin, A Snake Venom Disintegrin, Inhibits Angiogenesis Elicited by Basic Fibroblast Growth Factor and Suppresses Tumor Growth by A Selective _v3 Blockade of Endothelial Cells
Mol Pharmacol 2001 59: 1333-1342. [Abstract] [Full Text] [PDF]  

Tommi Nyrönen, Marjo Pihlavisto, Juha M. Peltonen, Anna-Marja Hoffrén, Minna Varis, Tiina Salminen, Siegfried Wurster, Anne Marjamäki, Liisa Kanerva, Erja Katainen, Leif Laaksonen, Juha-Matti Savola, Mika Scheinin, and Mark S. Johnson

Molecular Mechanism for Agonist-Promoted _2A-Adrenoceptor Activation by Norepinephrine and Epinephrine
Mol Pharmacol 2001 59: 1343-1354. [Abstract] [Full Text] [PDF]  

Errata:

Correction to "Mechanisms of agonist-induced down-regulation of the human -opioid receptor: internalization is required for down-regulation"
Mol Pharmacol 2001 59: 1355. [Full Text] [PDF]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.