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Other Issues:
July 2003; 64 (1)   [Index by Author]  [Cover Caption]
       Perspective
       Accelerated Communications
       Articles
       Errata
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Perspective:

Brinda K. Rana
New Insights into G-Protein-Coupled Receptor Signaling from the Melanocortin Receptor System
Mol Pharmacol 2003 64: 1-4. [Full Text] [PDF]  

Accelerated Communications:

J. Duncan Leever, Suzanne Clark, Autumn M. Weeks, and Kathryn M. Partin
Identification of a Site in GluR1 and GluR2 That Is Important for Modulation of Deactivation and Desensitization
Mol Pharmacol 2003 64: 5-10. [Abstract] [Full Text] [PDF]  

Articles:

Eric Elenko, Thierry Fischer, Ingrid Niesman, Tim Harding, Tammie McQuistan, Mark Von Zastrow, and Marilyn G. Farquhar
Spatial Regulation of G{alpha}i Protein Signaling in Clathrin-Coated Membrane Microdomains Containing GAIP
Mol Pharmacol 2003 64: 11-20. [Abstract] [Full Text] [PDF]  

Uta Voigtländer, Kirstin Jöhren, Marion Mohr, Alexandra Raasch, Christian Tränkle, Stefan Buller, John Ellis, Hans-Dieter Höltje, and Klaus Mohr
Allosteric Site on Muscarinic Acetylcholine Receptors: Identification of Two Amino Acids in the Muscarinic M2 Receptor That Account Entirely for the M2/M5 Subtype Selectivities of Some Structurally Diverse Allosteric Ligands in N-Methylscopolamine-Occupied Receptors
Mol Pharmacol 2003 64: 21-31. [Abstract] [Full Text] [PDF]  

Vipa Chaipatikul, Laurie J. Erickson-Herbrandson, Horace H. Loh, and Ping-Yee Law
Rescuing the Traffic-Deficient Mutants of Rat µ-Opioid Receptors with Hydrophobic Ligands
Mol Pharmacol 2003 64: 32-41. [Abstract] [Full Text] [PDF]  

Graham R. Robertson, Jacqueline Field, Bryan Goodwin, Sandra Bierach, Minh Tran, Anne Lehnert, and Christopher Liddle
Transgenic Mouse Models of Human CYP3A4 Gene Regulation
Mol Pharmacol 2003 64: 42-50. [Abstract] [Full Text] [PDF]  

Cristiano Ferlini, Giuseppina Raspaglio, Simona Mozzetti, Mariagrazia Distefano, Flavia Filippetti, Enrica Martinelli, Gabriella Ferrandina, Daniela Gallo, Franco Oreste Ranelletti, and Giovanni Scambia
Bcl-2 Down-Regulation Is a Novel Mechanism of Paclitaxel Resistance
Mol Pharmacol 2003 64: 51-58. [Abstract] [Full Text] [PDF]  

Sylvie Diochot, Erwann Loret, Thomas Bruhn, Lászlo Béress, and Michel Lazdunski
APETx1, a New Toxin from the Sea Anemone Anthopleura elegantissima, Blocks Voltage-Gated Human Ether-a-go-go–Related Gene Potassium Channels
Mol Pharmacol 2003 64: 59-69. [Abstract] [Full Text] [PDF]  

Guiscard Seebohm, Jun Chen, Nathalie Strutz, Chris Culberson, Christian Lerche, and Michael C. Sanguinetti
Molecular Determinants of KCNQ1 Channel Block by a Benzodiazepine
Mol Pharmacol 2003 64: 70-77. [Abstract] [Full Text] [PDF]  

Wha Bin Im, Christopher L. Chio, Glen L. Alberts, and Dac M. Dinh
Positive Allosteric Modulator of the Human 5-HT2C Receptor
Mol Pharmacol 2003 64: 78-84. [Abstract] [Full Text] [PDF]  

Angela Ianaro, Armando Ialenti, Pasquale Maffia, Paola Di Meglio, Massimo Di Rosa, and M. Gabriella Santoro
Anti-Inflammatory Activity of 15-Deoxy-{Delta}12,14-PGJ2 and 2-Cyclopenten-1-one: Role of the Heat Shock Response
Mol Pharmacol 2003 64: 85-93. [Abstract] [Full Text] [PDF]  

Yingkui Yang, Min Chen, Yumei Lai, Ira Gantz, Aydin Yagmurlu, Keith E. Georgeson, and Carroll M. Harmon
Molecular Determination of Agouti-Related Protein Binding to Human Melanocortin-4 Receptor
Mol Pharmacol 2003 64: 94-103. [Abstract] [Full Text] [PDF]  

Frederic Marteau, Emmanuel Le Poul, David Communi, Didier Communi, Catherine Labouret, Pierre Savi, Jean-Marie Boeynaems, and Nathalie Suarez Gonzalez
Pharmacological Characterization of the Human P2Y13 Receptor
Mol Pharmacol 2003 64: 104-112. [Abstract] [Full Text] [PDF]  

Sharon L. Ripp, K. Cameron Falkner, Mary L. Pendleton, Viola Tamasi, and Russell A. Prough
Regulation of CYP2C11 by Dehydroepiandrosterone and Peroxisome Proliferators: Identification of the Negative Regulatory Region of the Gene
Mol Pharmacol 2003 64: 113-122. [Abstract] [Full Text] [PDF]  

Mei-Chih Liang, Sujata Bardhan, Chaomin Li, Emily A. Pace, John A. Porco, Jr, and Thomas D. Gilmore
Jesterone Dimer, a Synthetic Derivative of the Fungal Metabolite Jesterone, Blocks Activation of Transcription Factor Nuclear Factor {kappa}B by Inhibiting the Inhibitor of {kappa}B Kinase
Mol Pharmacol 2003 64: 123-131. [Abstract] [Full Text] [PDF]  

Judith A. Enyeart, Sanjay Danthi, and John J. Enyeart
Corticotropin Induces the Expression of TREK-1 mRNA and K+ Current in Adrenocortical Cells
Mol Pharmacol 2003 64: 132-142. [Abstract] [Full Text] [PDF]  

Rachel Davis-Taber, Eduardo J. Molinari, Robert J. Altenbach, Kristi L. Whiteaker, Char-Chang Shieh, Gary Rotert, Steven A. Buckner, John Malysz, Ivan Milicic, Jeffrey S. McDermott, Gary A. Gintant, Michael J. Coghlan, William A. Carroll, Victoria E. Scott, and Murali Gopalakrishnan
[125I]A-312110, a Novel High-Affinity 1,4-Dihydropyridine ATP-sensitive K+ Channel Opener: Characterization and Pharmacology of Binding
Mol Pharmacol 2003 64: 143-153. [Abstract] [Full Text] [PDF]  

Nita J. Patel, Maciej J. Zamek-Gliszczynski, Peijin Zhang, Yong-Hae Han, Peter L. M. Jansen, Peter J. Meier, Bruno Stieger, and Kim L. R. Brouwer
Phenobarbital Alters Hepatic Mrp2 Function by Direct and Indirect Interactions
Mol Pharmacol 2003 64: 154-159. [Abstract] [Full Text] [PDF]  

Zdenek Dvorák, Martin Modriansky, Lydiane Pichard-Garcia, Patrick Balaguer, Marie-Jose Vilarem, Jitka Ulrichová, Patrick Maurel, and Jean-Marc Pascussi
Colchicine Down-Regulates Cytochrome P450 2B6, 2C8, 2C9, and 3A4 in Human Hepatocytes by Affecting Their Glucocorticoid Receptor-Mediated Regulation
Mol Pharmacol 2003 64: 160-169. [Abstract] [Full Text] [PDF]  

Kim S. Sugamori, Sharon Wong, Andrea Gaedigk, Violeta Yu, Hanan Abramovici, Richard Rozmahel, and Denis M. Grant
Generation and Functional Characterization of Arylamine N-Acetyltransferase Nat1/Nat2Double-Knockout Mice
Mol Pharmacol 2003 64: 170-179. [Abstract] [Full Text] [PDF]  

Christian Tränkle, Oliver Weyand, Uta Voigtländer, Anita Mynett, Sebastian Lazareno, Nigel J. M. Birdsall, and Klaus Mohr
Interactions of Orthosteric and Allosteric Ligands with [3H]Dimethyl-W84 at the Common Allosteric Site of Muscarinic M2 Receptors
Mol Pharmacol 2003 64: 180-190. [Abstract] [Full Text] [PDF]  

Errata:

Editors' Note regarding "Mechanism of corticotropin-releasing factor type I receptor regulation by nonpeptide antagonists"
Mol Pharmacol 2003 64: 191. [Full Text] [PDF]  

Correction to "Prostaglandin receptor EP4 mediates the bone anabolic effects of PGE2"
Mol Pharmacol 2003 64: 192. [Full Text] [PDF]  

Correction to "Spatial approximation between a photolabile residue in position 13 of secretin and the amino terminus of the secretin receptor"
Mol Pharmacol 2003 64: 193. [Full Text] [PDF]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.


Cover Caption:

Difference between the orientation of M2 wild-type Tyr177 and Gln177 in the ternary complex with NMS and diallylcaracurine V. See the article by Voigtländer et al. on page 21 of this issue.


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