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October 2003; 64 (4)   [Index by Author]  [Cover Caption]
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Minireview:

Eduardo R. Lazarowski, Richard C. Boucher, and T. Kendall Harden
Mechanisms of Release of Nucleotides and Integration of Their Action as P2X- and P2Y-Receptor Activating Molecules
Mol Pharmacol 2003 64: 785-795. [Full Text] [PDF]  

Perspective:

T. J. Murphy
Simple Nuclear Factor {kappa}B-Mediated µ-Opioid Receptor Induction in Immune Cells
Mol Pharmacol 2003 64: 796-797. [Full Text] [PDF]  

Articles:

Hervé Schaffhauser, Blake A. Rowe, Sylvia Morales, Laura E. Chavez-Noriega, Ruoyuan Yin, Christine Jachec, Sara P. Rao, Gretchen Bain, Anthony B. Pinkerton, Jean-Michel Vernier, Linda J. Bristow, Mark A. Varney, and Lorrie P. Daggett
Pharmacological Characterization and Identification of Amino Acids Involved in the Positive Modulation of Metabotropic Glutamate Receptor Subtype 2
Mol Pharmacol 2003 64: 798-810. [Abstract] [Full Text] [PDF]  

Shuei-Liong Lin, Ruey-Hwa Chen, Yung-Ming Chen, Wen-Chih Chiang, Tun-Jun Tsai, and Bor-Shen Hsieh
Pentoxifylline Inhibits Platelet-Derived Growth Factor-Stimulated Cyclin D1 Expression in Mesangial Cells by Blocking Akt Membrane Translocation
Mol Pharmacol 2003 64: 811-822. [Abstract] [Full Text] [PDF]  

Pari Malherbe, Nicole Kratochwil, Marie-Théeése Zenner, Jenny Piussi, Catherine Diener, Claudia Kratzeisen, Christophe Fischer, and Richard H. P. Porter
Mutational Analysis and Molecular Modeling of the Binding Pocket of the Metabotropic Glutamate 5 Receptor Negative Modulator 2-Methyl-6-(phenylethynyl)-pyridine
Mol Pharmacol 2003 64: 823-832. [Abstract] [Full Text] [PDF]  

Xinkang Wang, Xiang Li, Lin Xu, Yutian Zhan, Shoshanit Yaish-Ohad, Joseph A. Erhardt, Frank C. Barone, and Giora Z. Feuerstein
Up-Regulation of Secretory Leukocyte Protease Inhibitor (SLPI) in the Brain after Ischemic Stroke: Adenoviral Expression of SLPI Protects Brain from Ischemic Injury
Mol Pharmacol 2003 64: 833-840. [Abstract] [Full Text] [PDF]  

Yoe-Sik Bae, Ji Young Song, Youndong Kim, Rong He, Richard D. Ye, Jong-Young Kwak, Pann-Ghill Suh, and Sung Ho Ryu
Differential Activation of Formyl Peptide Receptor Signaling by Peptide Ligands
Mol Pharmacol 2003 64: 841-847. [Abstract] [Full Text] [PDF]  

Stephan Kellenberger, Ivan Gautschi, and Laurent Schild
Mutations in the Epithelial Na+ Channel ENaC Outer Pore Disrupt Amiloride Block by Increasing Its Dissociation Rate
Mol Pharmacol 2003 64: 848-856. [Abstract] [Full Text] [PDF]  

Zakaria Mtchedlishvili and Jaideep Kapur
A Presynaptic Action of the Neurosteroid Pregnenolone Sulfate on GABAergic Synaptic Transmission
Mol Pharmacol 2003 64: 857-864. [Abstract] [Full Text] [PDF]  

Anders A. Jensen, Ivan Mikkelsen, Bente Frølund, Hans Bräuner-Osborne, Erik Falch, and Povl Krogsgaard-Larsen
Carbamoylcholine Homologs: Novel and Potent Agonists at Neuronal Nicotinic Acetylcholine Receptors
Mol Pharmacol 2003 64: 865-875. [Abstract] [Full Text] [PDF]  

Jürgen Kraus, Christine Börner, Elisa Giannini, and Volker Höllt
The Role of Nuclear Factor {kappa}B in Tumor Necrosis Factor-Regulated Transcription of the Human µ-Opioid Receptor Gene
Mol Pharmacol 2003 64: 876-884. [Abstract] [Full Text] [PDF]  

Marina V. Skok, Elena N. Kalashnik, Ludmila N. Koval, Victor I. Tsetlin, Yuriy N. Utkin, Jean-Pierre Changeux, and Régis Grailhe
Functional Nicotinic Acetylcholine Receptors Are Expressed in B Lymphocyte-Derived Cell Lines
Mol Pharmacol 2003 64: 885-889. [Abstract] [Full Text] [PDF]  

Roxanne A. Ally, Kirk L. Ives, Elie Traube, Iman Eltounsi, Pei-Wen Chen, Patrick J. Cahill, James F. Battey, Mark R. Hellmich, and Glenn S. Kroog
Agonist- and Protein Kinase C-Induced Phosphorylation Have Similar Functional Consequences for Gastrin-Releasing Peptide Receptor Signaling via Gq
Mol Pharmacol 2003 64: 890-904. [Abstract] [Full Text] [PDF]  

Dan Wang, Scott L. Deken, Terri L. Whitworth, and Michael W. Quick
Syntaxin 1A Inhibits GABA Flux, Efflux, and Exchange Mediated by the Rat Brain GABA Transporter GAT1
Mol Pharmacol 2003 64: 905-913. [Abstract] [Full Text] [PDF]  

H. Vais, S. Atkinson, F. Pluteanu, S. J. Goodson, A. L. Devonshire, M. S. Williamson, and P. N. R. Usherwood
Mutations of the para Sodium Channel of Drosophila melanogaster Identify Putative Binding Sites for Pyrethroids
Mol Pharmacol 2003 64: 914-922. [Abstract] [Full Text] [PDF]  

Mandy Woods, Elizabeth G. Wood, Sonya C. Bardswell, David Bishop-Bailey, Stewart Barker, Stephen J. Wort, Jane A. Mitchell, and Timothy D. Warner
Role for Nuclear Factor-{kappa}B and Signal Transducer and Activator of Transcription 1/Interferon Regulatory Factor-1 in Cytokine-Induced Endothelin-1 Release in Human Vascular Smooth Muscle Cells
Mol Pharmacol 2003 64: 923-931. [Abstract] [Full Text] [PDF]  

Annamaria De Luca, Sophie Talon, Michela De Bellis, Jean-François Desaphy, Giovanni Lentini, Filomena Corbo, Antonio Scilimati, Carlo Franchini, Vincenzo Tortorella, and Diana Conte Camerino
Optimal Requirements for High Affinity and Use-Dependent Block of Skeletal Muscle Sodium Channel by N-Benzyl Analogs of Tocainide-Like Compounds
Mol Pharmacol 2003 64: 932-945. [Abstract] [Full Text] [PDF]  

Donald M. Kuhn and Timothy J. Geddes
Tetrahydrobiopterin Prevents Nitration of Tyrosine Hydroxylase by Peroxynitrite and Nitrogen Dioxide
Mol Pharmacol 2003 64: 946-953. [Abstract] [Full Text] [PDF]  

Tim J. Brier, Ian R. Mellor, Denis B. Tikhonov, Ioana Neagoe, Zuoyi Shao, Matt J. Brierley, Kristian Strømgaard, Jerzy W. Jaroszewski, Povl Krogsgaard-Larsen, and Peter N. R. Usherwood
Contrasting Actions of Philanthotoxin-343 and Philanthotoxin-(12) on Human Muscle Nicotinic Acetylcholine Receptors
Mol Pharmacol 2003 64: 954-964. [Abstract] [Full Text] [PDF]  

M. Huigsloot, R. B. Tijdens, and B. van de Water
Inhibition of Protein Kinase C{alpha} Enhances Anticancer Agent-Induced Loss of Anchorage-Independent Growth Regardless of Protection against Apoptosis by Bcl-2
Mol Pharmacol 2003 64: 965-973. [Abstract] [Full Text] [PDF]  

Amy M. Avila, Martha I. Dávila-García, Veronica S. Ascarrunz, YingxIan Xiao, and Kenneth J. Kellar
Differential Regulation of Nicotinic Acetylcholine Receptors in PC12 Cells by Nicotine and Nerve Growth Factor
Mol Pharmacol 2003 64: 974-986. [Abstract] [Full Text] [PDF]  

S. V. Penelope Jones
Role of the Small GTPase Rho in Modulation of the Inwardly Rectifying Potassium Channel Kir2.1.
Mol Pharmacol 2003 64: 987-993. [Abstract] [Full Text] [PDF]  

Hideo Ohta, Koichi Sato, Naoya Murata, Alatangaole Damirin, Enkhzol Malchinkhuu, Junko Kon, Takao Kimura, Masayuki Tobo, Yuji Yamazaki, Tomoko Watanabe, Mikio Yagi, Motoko Sato, Rika Suzuki, Hideko Murooka, Teruyuki Sakai, Tsuyoshi Nishitoba, Dong-Soon Im, Hiromi Nochi, Koichi Tamoto, Hideaki Tomura, and Fumikazu Okajima
Ki16425, a Subtype-Selective Antagonist for EDG-Family Lysophosphatidic Acid Receptors
Mol Pharmacol 2003 64: 994-1005. [Abstract] [Full Text] [PDF]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.


Cover Caption:

About the cover: Molecular modeling of the rmGlu5 complexed with MPEP. See the article by Malherbe et al. on page 823 of this issue.


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