Minireview:

Roya Zoraghi, Jackie D. Corbin, and Sharron H. Francis

Properties and Functions of GAF Domains in Cyclic Nucleotide Phosphodiesterases and Other Proteins
Mol Pharmacol 2004 65: 267-278. [Full Text] [PDF]  

Perspectives:

Erin G. Schuetz

Lessons from the CYP3A4 Promoter
Mol Pharmacol 2004 65: 279-281. [Full Text] [PDF]  

Articles:

Attila Tóth, Peter M. Blumberg, Zili Chen, and Alan P. Kozikowski

Design of a High-Affinity Competitive Antagonist of the Vanilloid Receptor Selective for the Calcium Entry-Linked Receptor Population
Mol Pharmacol 2004 65: 282-291. [Abstract] [Full Text] [PDF]  

Simrat P. S. Saini, Junichiro Sonoda, Li Xu, David Toma, Hirdesh Uppal, Ying Mu, Songrong Ren, David D. Moore, Ronald M. Evans, and Wen Xie

A Novel Constitutive Androstane Receptor-Mediated and CYP3A-Independent Pathway of Bile Acid Detoxification
Mol Pharmacol 2004 65: 292-300. [Abstract] [Full Text] [PDF]  

Michael J. Sorich, John O. Miners, Ross A. McKinnon, and Paul A. Smith

Multiple Pharmacophores for the Investigation of Human UDP-Glucuronosyltransferase Isoform Substrate Selectivity
Mol Pharmacol 2004 65: 301-308. [Abstract] [Full Text] [PDF]  

Kimberlee S. Mix, Charles I. Coon, Evan D. Rosen, Nanjoo Suh, Michael B. Sporn, and Constance E. Brinckerhoff

Peroxisome Proliferator-Activated Receptor--Independent Repression of Collagenase Gene Expression by 2-Cyano-3,12-dioxooleana-1,9-dien-28-oic Acid and Prostaglandin 15-Deoxy-(12,14) J₂: A Role for Smad Signaling
Mol Pharmacol 2004 65: 309-318. [Abstract] [Full Text] [PDF]  

Samuel H. H. Chan, Kui-Fen Chang, Chen-Chun Ou, and Julie Y. H. Chan

Nitric Oxide Regulates c-fos Expression in Nucleus Tractus Solitarii Induced by Baroreceptor Activation via cGMP-Dependent Protein Kinase and cAMP Response Element-Binding Protein Phosphorylation
Mol Pharmacol 2004 65: 319-325. [Abstract] [Full Text] [PDF]  

Keiko Matsumura, Tetsuya Saito, Yoshiki Takahashi, Takeshi Ozeki, Kazuma Kiyotani, Masaki Fujieda, Hiroshi Yamazaki, Hideo Kunitoh, and Tetsuya Kamataki

Identification of a Novel Polymorphic Enhancer of the Human CYP3A4 Gene
Mol Pharmacol 2004 65: 326-334. [Abstract] [Full Text] [PDF]  

Gilles Crambert, Daniele Schaer, Sophie Roy, and Käthi Geering

New Molecular Determinants Controlling the Accessibility of Ouabain to Its Binding Site in Human Na,K-ATPase Isoforms
Mol Pharmacol 2004 65: 335-341. [Abstract] [Full Text] [PDF]  

Zoltán H. Németh, Hector R. Wong, Kelli Odoms, Edwin A. Deitch, Csaba Szabó, E. Sylvester Vizi, and György Haskó

Proteasome Inhibitors Induce Inhibitory B (IB) Kinase Activation, IB Degradation, and Nuclear Factor B Activation in HT-29 Cells
Mol Pharmacol 2004 65: 342-349. [Abstract] [Full Text] [PDF]  

Matjaz Humar, Soeren E. Pischke, Torsten Loop, Alexander Hoetzel, Rene Schmidt, Christoph Klaas, Heike L. Pahl, Klaus K. Geiger, and Benedikt H. J. Pannen

Barbiturates Directly Inhibit the Calmodulin/Calcineurin Complex: a Novel Mechanism of Inhibition of Nuclear Factor of Activated T Cells
Mol Pharmacol 2004 65: 350-361. [Abstract] [Full Text] [PDF]  

Bryan N. Becker, Hui-fang Cheng, Timothy G. Hammond, and Raymond C. Harris

The Type 1 Angiotensin II Receptor Tail Affects Receptor Targeting, Internalization, and Membrane Fusion Properties
Mol Pharmacol 2004 65: 362-369. [Abstract] [Full Text] [PDF]  

Chung-Chin Kuo, Bei-Jung Lin, Huai-Ren Chang, and Chi-Pan Hsieh

Use-Dependent Inhibition of the N-Methyl-D-aspartate Currents by Felbamate: a Gating Modifier with Selective Binding to the Desensitized Channels
Mol Pharmacol 2004 65: 370-380. [Abstract] [Full Text] [PDF]  

R. A. Bannister, K. Melliti, and B. A. Adams

Differential Modulation of Ca_V2.3 Ca²⁺ Channels by Gq/11-Coupled Muscarinic Receptors
Mol Pharmacol 2004 65: 381-388. [Abstract] [Full Text] [PDF]  

Jörg H. W. Distler, Claudia Hagen, Astrid Hirth, Ulf Müller-Ladner, Hanns M. Lorenz, Angela del Rosso, Beat A. Michel, Renate E. Gay, Ratanavadee Nanagara, Kusuki Nishioka, Marco Matucci-Cerinic, Joachim R. Kalden, Steffen Gay, and Oliver Distler

Bucillamine Induces the Synthesis of Vascular Endothelial Growth Factor Dose-Dependently in Systemic Sclerosis Fibroblasts via Nuclear Factor-B and Simian Virus 40 Promoter Factor 1 Pathways
Mol Pharmacol 2004 65: 389-399. [Abstract] [Full Text] [PDF]  

Wing Lam, Ying Li, Jieh-Yuan Liou, Ginger E. Dutschman, and Yung-chi Cheng

Reverse Transcriptase Activity of Hepatitis B Virus (HBV) DNA Polymerase within Core Capsid: Interaction with Deoxynucleoside Triphosphates and Anti-HBV L-Deoxynucleoside Analog Triphosphates
Mol Pharmacol 2004 65: 400-406. [Abstract] [Full Text] [PDF]  

Andreas Papapetropoulos, David Fulton, Michelle I. Lin, Jason Fontana, Timothy J. McCabe, Stefan Zoellner, Guillermo García-Cardeña, Zongmin Zhou, Jean-Phillipe Gratton, and William C. Sessa

Vanadate Is a Potent Activator of Endothelial Nitric-Oxide Synthase: Evidence for the Role of the Serine/Threonine Kinase Akt and the 90-kDa Heat Shock Protein
Mol Pharmacol 2004 65: 407-415. [Abstract] [Full Text] [PDF]  

Maria Backlund and Magnus Ingelman-Sundberg

Different Structural Requirements of the Ligand Binding Domain of the Aryl Hydrocarbon Receptor for High- and Low-Affinity Ligand Binding and Receptor Activation
Mol Pharmacol 2004 65: 416-425. [Abstract] [Full Text] [PDF]  

Gary L. Waldo and T. Kendall Harden

Agonist Binding and Gq-Stimulating Activities of the Purified Human P2Y₁ Receptor
Mol Pharmacol 2004 65: 426-436. [Abstract] [Full Text] [PDF] Correction  

Karen Beagles, Anton Wellstein, and Barbara Bayer

Systemic Morphine Administration Suppresses Genes Involved in Antigen Presentation
Mol Pharmacol 2004 65: 437-442. [Abstract] [Full Text] [PDF]  

Marco Gruss, Trevor J. Bushell, Damian P. Bright, William R. Lieb, Alistair Mathie, and Nicholas P. Franks

Two-Pore-Domain K⁺ Channels Are a Novel Target for the Anesthetic Gases Xenon, Nitrous Oxide, and Cyclopropane
Mol Pharmacol 2004 65: 443-452. [Abstract] [Full Text] [PDF]  

Elizabeth R. Baker, Ruud Zwart, Emanuele Sher, and Neil S. Millar

Pharmacological Properties of 910 Nicotinic Acetylcholine Receptors Revealed by Heterologous Expression of Subunit Chimeras
Mol Pharmacol 2004 65: 453-460. [Abstract] [Full Text] [PDF]  

Aviva Levine-Fridman, Li Chen, and Cornelis J. Elferink

Cytochrome P4501A1 Promotes G₁ Phase Cell Cycle Progression by Controlling Aryl Hydrocarbon Receptor Activity
Mol Pharmacol 2004 65: 461-469. [Abstract] [Full Text] [PDF]  

Randy C. Mifflin, Jamal I. Saada, John F. Di Mari, John D. Valentich, Patrick A. Adegboyega, and Don W. Powell

Aspirin-Mediated COX-2 Transcript Stabilization via Sustained p38 Activation in Human Intestinal Myofibroblasts
Mol Pharmacol 2004 65: 470-478. [Abstract] [Full Text] [PDF]  

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