Perspectives:

Colleen A. Flanagan

A GPCR That Is Not "DRY"
Mol Pharmacol 2005 68: 1-3. Published online April 26, 2005; 10.1124/mol.105.014183 [Abstract] [Full Text] [PDF]  

Accelerated Communications:

John J. Crowley, Steven N. Treistman, and Alejandro M. Dopico

Distinct Structural Features of Phospholipids Differentially Determine Ethanol Sensitivity and Basal Function of BK Channels
Mol Pharmacol 2005 68: 4-10. Published online April 22, 2005; 10.1124/mol.105.012971 [Abstract] [Full Text] [PDF]  

Articles:

Mette M. Rosenkilde, Thomas N. Kledal, and Thue W. Schwartz

High Constitutive Activity of a Virus-Encoded Seven Transmembrane Receptor in the Absence of the Conserved DRY Motif (Asp-Arg-Tyr) in Transmembrane Helix 3
Mol Pharmacol 2005 68: 11-19. Published online March 23, 2005; 10.1124/mol.105.011239 [Abstract] [Full Text] [PDF]  

Vincent Setola, Malgorzata Dukat, Richard A. Glennon, and Bryan L. Roth

Molecular Determinants for the Interaction of the Valvulopathic Anorexigen Norfenfluramine with the 5-HT_2B Receptor
Mol Pharmacol 2005 68: 20-33. Published online April 14, 2005; 10.1124/mol.104.009266 [Abstract] [Full Text] [PDF]  

Myungsa Kang, Godfrey Lisk, Stephen Hollingworth, Stephen M. Baylor, and Sanjay A. Desai

Malaria Parasites Are Rapidly Killed by Dantrolene Derivatives Specific for the Plasmodial Surface Anion Channel
Mol Pharmacol 2005 68: 34-40. Published online April 20, 2005; 10.1124/mol.104.010553 [Abstract] [Full Text] [PDF]  

Ursula G. B. Haider, Thomas U. Roos, Maria I. Kontaridis, Benjamin G. Neel, Dan Sorescu, Kathy K. Griendling, Angelika M. Vollmar, and Verena M. Dirsch

Resveratrol Inhibits Angiotensin II- and Epidermal Growth Factor-Mediated Akt Activation: Role of Gab1 and Shp2
Mol Pharmacol 2005 68: 41-48. Published online April 22, 2005; 10.1124/mol.104.005421 [Abstract] [Full Text] [PDF]  

Jan Balzarini, Joeri Auwerx, Fátima Rodríguez-Barrios, Allel Chedad, Viktor Farkas, Francesca Ceccherini-Silberstein, Carlos García-Aparicio, Sonsoles Velázquez, Erik De Clercq, Carlo-Federico Perno, María-José Camarasa, and Federico Gago

The Amino Acid Asn136 in HIV-1 Reverse Transcriptase (RT) Maintains Efficient Association of Both RT Subunits and Enables the Rational Design of Novel RT Inhibitors
Mol Pharmacol 2005 68: 49-60. Published online April 15, 2005; 10.1124/mol.105.012435 [Abstract] [Full Text] [PDF]  

James M. Sonner, Mike Cascio, Yilei Xing, Michael S. Fanselow, Jason E. Kralic, A. Leslie Morrow, Esa R. Korpi, Steven Hardy, Brian Sloat, Edmond I. Eger, II, and Gregg E. Homanics

1 Subunit-Containing GABA Type A Receptors in Forebrain Contribute to the Effect of Inhaled Anesthetics on Conditioned Fear
Mol Pharmacol 2005 68: 61-68. Published online April 15, 2005; 10.1124/mol.104.009936 [Abstract] [Full Text] [PDF]  

Rundong Zhang, Dow P. Hurst, Judy Barnett-Norris, Patricia H. Reggio, and Zhao-Hui Song

Cysteine 2.59(89) in the Second Transmembrane Domain of Human CB2 Receptor Is Accessible within the Ligand Binding Crevice: Evidence for Possible CB2 Deviation from a Rhodopsin Template
Mol Pharmacol 2005 68: 69-83. Published online April 19, 2005; 10.1124/mol.104.007823 [Abstract] [Full Text] [PDF]  

I. Nikonenko, M. Bancila, A. Bloc, D. Muller, and P. Bijlenga

Inhibition of T-Type Calcium Channels Protects Neurons from Delayed Ischemia-Induced Damage
Mol Pharmacol 2005 68: 84-89. Published online April 25, 2005; 10.1124/mol.104.010066 [Abstract] [Full Text] [PDF]  

Qisheng Liu, Renzo Cescato, Dian A. Dewi, Jean Rivier, Jean-Claude Reubi, and Agnes Schonbrunn

Receptor Signaling and Endocytosis Are Differentially Regulated by Somatostatin Analogs
Mol Pharmacol 2005 68: 90-101. Published online April 26, 2005; 10.1124/mol.105.011767 [Abstract] [Full Text] [PDF]  

B. G. Garcia, Y. Wei, J. A. Moron, R. Z. Lin, J. A. Javitch, and A. Galli

Akt Is Essential for Insulin Modulation of Amphetamine-Induced Human Dopamine Transporter Cell-Surface Redistribution
Mol Pharmacol 2005 68: 102-109. Published online March 28, 2005; 10.1124/mol.104.009092 [Abstract] [Full Text] [PDF]  

Elisa Giovannetti, Valentina Mey, Sara Nannizzi, Giuseppe Pasqualetti, Luca Marini, Mario Del Tacca, and Romano Danesi

Cellular and Pharmacogenetics Foundation of Synergistic Interaction of Pemetrexed and Gemcitabine in Human Non–Small-Cell Lung Cancer Cells
Mol Pharmacol 2005 68: 110-118. Published online March 28, 2005; 10.1124/mol.104.009373 [Abstract] [Full Text] [PDF]  

Sudhakar Chintharlapalli, Sabitha Papineni, Marina Konopleva, Michael Andreef, Ismael Samudio, and Stephen Safe

2-Cyano-3,12-dioxoolean-1,9-dien-28-oic Acid and Related Compounds Inhibit Growth of Colon Cancer Cells through Peroxisome Proliferator-Activated Receptor -Dependent and -Independent Pathways
Mol Pharmacol 2005 68: 119-128. Published online March 29, 2005; 10.1124/mol.105.011437 [Abstract] [Full Text] [PDF]  

Sundeep Malik, Mousumi Ghosh, Tabetha M. Bonacci, Gregory G. Tall, and Alan V. Smrcka

Ric-8 Enhances G Protein -Dependent Signaling in Response to -Binding Peptides in Intact Cells
Mol Pharmacol 2005 68: 129-136. Published online March 31, 2005; 10.1124/mol.104.010116 [Abstract] [Full Text] [PDF]  

Martin Gassmann, Corinne Haller, Yanick Stoll, Said Abdel Aziz, Barbara Biermann, Johannes Mosbacher, Klemens Kaupmann, and Bernhard Bettler

The RXR-Type Endoplasmic Reticulum-Retention/Retrieval Signal of GABA_B1 Requires Distant Spacing from the Membrane to Function
Mol Pharmacol 2005 68: 137-144. Published online April 1, 2005; 10.1124/mol.104.010256 [Abstract] [Full Text] [PDF]  

Hiroyasu Sakai, Yoshihiko Chiba, Tomona Hirano, and Miwa Misawa

Possible Involvement of CPI-17 in Augmented Bronchial Smooth Muscle Contraction in Antigen-Induced Airway Hyper-Responsive Rats
Mol Pharmacol 2005 68: 145-151. Published online April 6, 2005; 10.1124/mol.104.004325 [Abstract] [Full Text] [PDF]  

Zi-Wei Chen, Chang-Sheng S. Chang, Tarek A. Leil, Riccardo Olcese, and Richard W. Olsen

GABA_A Receptor-Associated Protein Regulates GABA_A Receptor Cell-Surface Number in Xenopus laevis Oocytes
Mol Pharmacol 2005 68: 152-159. Published online April 6, 2005; 10.1124/mol.104.009878 [Abstract] [Full Text] [PDF]  

Martin G. Belinsky, Paul A. Dawson, Irina Shchaveleva, Lisa J. Bain, Renxue Wang, Victor Ling, Zhe-Sheng Chen, Alex Grinberg, Heiner Westphal, Andres Klein-Szanto, Anthony Lerro, and Gary D. Kruh

Analysis of the In Vivo Functions of Mrp3
Mol Pharmacol 2005 68: 160-168. Published online April 6, 2005; 10.1124/mol.104.010587 [Abstract] [Full Text] [PDF]  

Elicia B. E. Berry, Jeffrey A. Keelan, Rachel J. A. Helliwell, R. Stewart Gilmour, and Murray D. Mitchell

Nanomolar and Micromolar Effects of 15-Deoxy-^12,14-prostaglandin J₂ on Amnion-Derived WISH Epithelial Cells: Differential Roles of Peroxisome Proliferator-Activated Receptors and and Nuclear Factor B
Mol Pharmacol 2005 68: 169-178. Published online April 8, 2005; 10.1124/mol.104.009449 [Abstract] [Full Text] [PDF]  

Faith C. H. Li, Julie Y. H. Chan, Samuel H. H. Chan, and Alice Y. W. Chang

In the Rostral Ventrolateral Medulla, the 70-kDa Heat Shock Protein (HSP70), but Not HSP90, Confers Neuroprotection against Fatal Endotoxemia via Augmentation of Nitric-Oxide Synthase I (NOS I)/Protein Kinase G Signaling Pathway and Inhibition of NOS II/Peroxynitrite Cascade
Mol Pharmacol 2005 68: 179-192. Published online April 12, 2005; 10.1124/mol.105.011684 [Abstract] [Full Text] [PDF]  

Alfonso Lampen, Paul A. Grimaldi, and Heinz Nau

Modulation of Peroxisome Proliferator-Activated Receptor Activity Affects Neural Cell Adhesion Molecule and Polysialyltransferase ST8SiaIV Induction by Teratogenic Valproic Acid Analogs in F9 Cell Differentiation
Mol Pharmacol 2005 68: 193-203. Published online April 13, 2005; 10.1124/mol.104.009340 [Abstract] [Full Text] [PDF]  

Dongyi Du, Bruce M. Raaka, Hagit Grimberg, Monica Lupu-Meiri, Yoram Oron, and Marvin C. Gershengorn

Carboxyl Tail Cysteine Mutants of the Thyrotropin-Releasing Hormone Receptor Type 1 Exhibit Constitutive Signaling: Role of Palmitoylation
Mol Pharmacol 2005 68: 204-209. Published online April 15, 2005; 10.1124/mol.105.012641 [Abstract] [Full Text] [PDF]  

Qing Yang, Regina Alemany, Jesús Casas, Klára Kitajka, Stephen M. Lanier, and Pablo V. Escribá

Influence of the Membrane Lipid Structure on Signal Processing via G Protein-Coupled Receptors
Mol Pharmacol 2005 68: 210-217. Published online April 18, 2005; 10.1124/mol.105.011692 [Abstract] [Full Text] [PDF]  

M. Wood, M. Ananthanarayanan, B. Jones, R. Wooton-Kee, T. Hoffman, F. J. Suchy, and M. Vore

Hormonal Regulation of Hepatic Organic Anion Transporting Polypeptides
Mol Pharmacol 2005 68: 218-225. Published online April 19, 2005; 10.1124/mol.104.010371 [Abstract] [Full Text] [PDF]  

Biljana Musicki, Hunter C. Champion, Robyn E. Becker, Tongyun Liu, Melissa F. Kramer, and Arthur L. Burnett

Erection Capability Is Potentiated by Long-Term Sildenafil Treatment: Role of Blood Flow-Induced Endothelial Nitric-Oxide Synthase Phosphorylation
Mol Pharmacol 2005 68: 226-232. Published online April 25, 2005; 10.1124/mol.104.010678 [Abstract] [Full Text] [PDF]  

Brian P. Delisle, Jessica K. Slind, Jennifer A. Kilby, Corey L. Anderson, Blake D. Anson, Ravi C. Balijepalli, David J. Tester, Michael J. Ackerman, Timothy J. Kamp, and Craig T. January

Intragenic Suppression of Trafficking-Defective KCNH2 Channels Associated with Long QT Syndrome
Mol Pharmacol 2005 68: 233-240. Published online April 25, 2005; 10.1124/mol.105.012914 [Abstract] [Full Text] [PDF] Data Supplement  

Nael Nadif Kasri, Geert Bultynck, Jan B. Parys, Geert Callewaert, Ludwig Missiaen, and Humbert De Smedt

Suramin and Disulfonated Stilbene Derivatives Stimulate the Ca²⁺-Induced Ca²⁺-Release Mechanism in A7r5 Cells
Mol Pharmacol 2005 68: 241-250. Published online April 25, 2005; 10.1124/mol.105.013045 [Abstract] [Full Text] [PDF]  

Hiromichi Fujino, Sambhitab Salvi, and John W. Regan

Differential Regulation of Phosphorylation of the cAMP Response Element-Binding Protein after Activation of EP₂ and EP₄ Prostanoid Receptors by Prostaglandin E₂
Mol Pharmacol 2005 68: 251-259. Published online April 26, 2005; 10.1124/mol.105.011833 [Abstract] [Full Text] [PDF]  

Errata:

Editor's Note Regarding "Mechanism of Corticotropin-Releasing Factor Type I Receptor Regulation by Nonpeptide Antagonists"
Mol Pharmacol 2005 68: 260. [Full Text] [PDF]  

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