Perspectives:

Henning Schröder

No Nitric Oxide for HO-1 from Sodium Nitroprusside
Mol Pharmacol 2006 69: 1507-1509. Published online February 13, 2006; 10.1124/mol.106.023416 [Abstract] [Full Text] [PDF] [Related Article] [Erratum]   

Zhihong Zhang and Kathryn E. Meier

New Assignments for Multitasking Signal Transduction Inhibitors
Mol Pharmacol 2006 69: 1510-1512. Published online February 23, 2006; 10.1124/mol.106.023721 [Abstract] [Full Text] [PDF] [Related Article]   

Accelerated Communications:

Ching Y. Wang, Chia W. Li, J. Don Chen, and William J. Welsh

Structural Model Reveals Key Interactions in the Assembly of the Pregnane X Receptor/Corepressor Complex
Mol Pharmacol 2006 69: 1513-1517. Published online February 1, 2006; 10.1124/mol.106.022368 [Abstract] [Full Text] [PDF]  

Articles:

Neena Kushwaha, Shannon C. Harwood, Ariel M. Wilson, Miles Berger, Laurence H. Tecott, Bryan L. Roth, and Paul R. Albert

Molecular Determinants in the Second Intracellular Loop of the 5-Hydroxytryptamine-1A Receptor for G-Protein Coupling
Mol Pharmacol 2006 69: 1518-1526. Published online January 12, 2006; 10.1124/mol.105.019844 [Abstract] [Full Text] [PDF] [Data Supplement]   

Zhengming Chen, Francis Y. Lee, Kapil N. Bhalla, and Jie Wu

Potent Inhibition of Platelet-Derived Growth Factor-Induced Responses in Vascular Smooth Muscle Cells by BMS-354825 (Dasatinib)
Mol Pharmacol 2006 69: 1527-1533. Published online January 25, 2006; 10.1124/mol.105.020172 [Abstract] [Full Text] [PDF]  

Eric B. Harstad, Christopher A. Guite, Tami L. Thomae, and Christopher A. Bradfield

Liver Deformation in Ahr-Null Mice: Evidence for Aberrant Hepatic Perfusion In Early Development
Mol Pharmacol 2006 69: 1534-1541. Published online January 27, 2006; 10.1124/mol.105.020107 [Abstract] [Full Text] [PDF]  

Huankai Hu, Christopher J. Endres, Cheng Chang, Nagavedi S. Umapathy, Eun-Woo Lee, You-Jun Fei, Shirou Itagaki, Peter W. Swaan, Vadivel Ganapathy, and Jashvant D. Unadkat

Electrophysiological Characterization and Modeling of the Structure Activity Relationship of the Human Concentrative Nucleoside Transporter 3 (hCNT3)
Mol Pharmacol 2006 69: 1542-1553. Published online January 30, 2006; 10.1124/mol.105.018945 [Abstract] [Full Text] [PDF]  

A. L. Slitt, N. J. Cherrington, M. Z. Dieter, L. M. Aleksunes, G. L. Scheffer, W. Huang, D. D. Moore, and C. D. Klaassen

trans-Stilbene Oxide Induces Expression of Genes Involved in Metabolism and Transport in Mouse Liver via CAR and Nrf2 Transcription Factors
Mol Pharmacol 2006 69: 1554-1563. Published online January 31, 2006; 10.1124/mol.105.014571 [Abstract] [Full Text] [PDF]  

Chih-Cheng Yang, Chia-Yu Ku, Shuo Wei, Chung-Wai Shiau, Chang-Shi Chen, Joseph J. Pinzone, Mathew D. Ringel, and Ching-Shih Chen

Peroxisome Proliferator-Activated Receptor -Independent Repression of Prostate-Specific Antigen Expression by Thiazolidinediones in Prostate Cancer Cells
Mol Pharmacol 2006 69: 1564-1570. Published online February 1, 2006; 10.1124/mol.105.018333 [Abstract] [Full Text] [PDF]  

Catalin M. Filipeanu, Fuguo Zhou, Erin K. Fugetta, and Guangyu Wu

Differential Regulation of the Cell-Surface Targeting and Function of - and ₁-Adrenergic Receptors by Rab1 GTPase in Cardiac Myocytes
Mol Pharmacol 2006 69: 1571-1578. Published online February 3, 2006; 10.1124/mol.105.019984 [Abstract] [Full Text] [PDF]  

Iraide Alloza, Andy Baxter, Qian Chen, Rune Matthiesen, and Koen Vandenbroeck

Celecoxib Inhibits Interleukin-12 and ₂ Folding and Secretion by a Novel COX2-Independent Mechanism Involving Chaperones of the Endoplasmic Reticulum
Mol Pharmacol 2006 69: 1579-1587. Published online February 7, 2006; 10.1124/mol.105.020669 [Abstract] [Full Text] [PDF]  

Taka-aki Koshimizu, Karla Kretschmannova, Mu-Lan He, Susumu Ueno, Akito Tanoue, Nobuyuki Yanagihara, Stanko S. Stojilkovic, and Gozoh Tsujimoto

Carboxyl-Terminal Splicing Enhances Physical Interactions between the Cytoplasmic Tails of Purinergic P2X Receptors
Mol Pharmacol 2006 69: 1588-1598. Published online February 8, 2006; 10.1124/mol.105.019802 [Abstract] [Full Text] [PDF]  

Darrell R. Boverhof, Joshua C. Kwekel, Daryl G. Humes, Lyle D. Burgoon, and Timothy R. Zacharewski

Dioxin Induces an Estrogen-Like, Estrogen Receptor-Dependent Gene Expression Response in the Murine Uterus
Mol Pharmacol 2006 69: 1599-1606. Published online February 8, 2006; 10.1124/mol.105.019638 [Abstract] [Full Text] [PDF] [Data Supplement]   

Wing Lam, Shin-Young Park, Chung-Hang Leung, and Yung-Chi Cheng

Apurinic/Apyrimidinic Endonuclease-1 Protein Level Is Associated with the Cytotoxicity of L-Configuration Deoxycytidine Analogs (Troxacitabine and -L-2',3'-Dideoxy-2',3'-didehydro-5-fluorocytidine) but Not D-Configuration Deoxycytidine Analogs (Gemcitabine and -D-Arabinofuranosylcytosine)
Mol Pharmacol 2006 69: 1607-1614. Published online February 15, 2006; 10.1124/mol.105.021527 [Abstract] [Full Text] [PDF] [Data Supplement]   

Sabine Olivier, Pierre Close, Emilie Castermans, Laurence de Leval, Sebastien Tabruyn, Alain Chariot, Michel Malaise, Marie-Paule Merville, Vincent Bours, and Nathalie Franchimont

Raloxifene-Induced Myeloma Cell Apoptosis: A Study of Nuclear Factor-B Inhibition and Gene Expression Signature
Mol Pharmacol 2006 69: 1615-1623. Published online February 23, 2006; 10.1124/mol.105.020479 [Abstract] [Full Text] [PDF]  

Keith Thompson, Michael J. Rogers, Fraser P. Coxon, and Julie C. Crockett

Cytosolic Entry of Bisphosphonate Drugs Requires Acidification of Vesicles after Fluid-Phase Endocytosis
Mol Pharmacol 2006 69: 1624-1632. Published online February 24, 2006; 10.1124/mol.105.020776 [Abstract] [Full Text] [PDF]  

Hye Jung Kim, Irina Tsoy, Min Kyu Park, Young Soo Lee, Jae Heun Lee, Han Geuk Seo, and Ki Churl Chang

Iron Released by Sodium Nitroprusside Contributes to Heme Oxygenase-1 Induction via the cAMP-Protein Kinase A-Mitogen-Activated Protein Kinase Pathway in RAW 264.7 Cells
Mol Pharmacol 2006 69: 1633-1640. Published online January 26, 2006; 10.1124/mol.105.020487 [Abstract] [Full Text] [PDF]  

Carole Fruchart-Gaillard, Gilles Mourier, Catherine Marquer, André Ménez, and Denis Servent

Identification of Various Allosteric Interaction Sites on M₁ Muscarinic Receptor Using ¹²⁵I-Met35-Oxidized Muscarinic Toxin 7
Mol Pharmacol 2006 69: 1641-1651. Published online January 26, 2006; 10.1124/mol.105.020883 [Abstract] [Full Text] [PDF]  

Jean-Yves Springael, Phu Nguyen Le Minh, Eneko Urizar, Sabine Costagliola, Gilbert Vassart, and Marc Parmentier

Allosteric Modulation of Binding Properties between Units of Chemokine Receptor Homo- and Hetero-Oligomers
Mol Pharmacol 2006 69: 1652-1661. Published online February 7, 2006; 10.1124/mol.105.019414 [Abstract] [Full Text] [PDF]  

Huan Lou, Shouying Du, Qing Ji, and Andrew Stolz

Induction of AKR1C2 by Phase II Inducers: Identification of a Distal Consensus Antioxidant Response Element Regulated by NRF2
Mol Pharmacol 2006 69: 1662-1672. Published online February 14, 2006; 10.1124/mol.105.019794 [Abstract] [Full Text] [PDF]  

Rita Restano-Cassulini, Yuliya V. Korolkova, Sylvie Diochot, Georgina Gurrola, Leonardo Guasti, Lourival D. Possani, Michel Lazdunski, Eugene V. Grishin, Annarosa Arcangeli, and Enzo Wanke

Species Diversity and Peptide Toxins Blocking Selectivity of Ether-à-go-go-Related Gene Subfamily K⁺ Channels in the Central Nervous System
Mol Pharmacol 2006 69: 1673-1683. Published online February 23, 2006; 10.1124/mol.105.019729 [Abstract] [Full Text] [PDF]  

Noboru Yamashita, Toshihiko Kaku, Tomoko Uchino, Shojiro Isomoto, Hironobu Yoshimatsu, and Katsushige Ono

Short- and Long-Term Amiodarone Treatments Regulate Ca_v3.2 Low-Voltage-Activated T-type Ca²⁺ Channel through Distinct Mechanisms
Mol Pharmacol 2006 69: 1684-1691. Published online January 27, 2006; 10.1124/mol.105.021253 [Abstract] [Full Text] [PDF]  

Susan J. Ormond, Nelson P. Barrera, Omar S. Qureshi, Robert M. Henderson, J. Michael Edwardson, and Ruth D. Murrell-Lagnado

An Uncharged Region within the N Terminus of the P2X₆ Receptor Inhibits Its Assembly and Exit from the Endoplasmic Reticulum
Mol Pharmacol 2006 69: 1692-1700. Published online February 1, 2006; 10.1124/mol.105.020404 [Abstract] [Full Text] [PDF] [Data Supplement]   

Mariem El Sayah, Rodrigo Medeiros, Elizabeth S. Fernandes, Maria M. Campos, and João B. Calixto

Mechanisms Underlying Lipopolysaccharide-Induced Kinin B₁ Receptor Up-Regulation in the Pig Iris Sphincter in Vitro
Mol Pharmacol 2006 69: 1701-1708. Published online February 7, 2006; 10.1124/mol.105.021097 [Abstract] [Full Text] [PDF]  

Kaichiro Kamiya, Ryoko Niwa, John S. Mitcheson, and Michael C. Sanguinetti

Molecular Determinants of hERG Channel Block
Mol Pharmacol 2006 69: 1709-1716. Published online February 10, 2006; 10.1124/mol.105.020990 [Abstract] [Full Text] [PDF]  

Kaoru Hazeki, Sachiko Kinoshita, Takayo Matsumura, Kiyomi Nigorikawa, Hiroshi Kubo, and Osamu Hazeki

Opposite Effects of Wortmannin and 2-(4-Morpholinyl)-8-phenyl-1(4H)-benzopyran-4-one Hydrochloride on Toll-Like Receptor-Mediated Nitric Oxide Production: Negative Regulation of Nuclear Factor-B by Phosphoinositide 3-Kinase
Mol Pharmacol 2006 69: 1717-1724. Published online February 10, 2006; 10.1124/mol.105.021162 [Abstract] [Full Text] [PDF]  

Karin Kohlstedt, Cynthia Gershome, Matthias Friedrich, Werner Muller-Esterl, François Alhenc-Gelas, Rudi Busse, and Ingrid Fleming

Angiotensin-Converting Enzyme (ACE) Dimerization Is the Initial Step in the ACE Inhibitor-Induced ACE Signaling Cascade in Endothelial Cells
Mol Pharmacol 2006 69: 1725-1732. Published online February 13, 2006; 10.1124/mol.105.020636 [Abstract] [Full Text] [PDF]  

Takao Masaki, Noriaki Yasokawa, Masanori Tohnishi, Tetsuyoshi Nishimatsu, Kenji Tsubata, Kazuyoshi Inoue, Kazuhiko Motoba, and Takashi Hirooka

Flubendiamide, a Novel Ca²⁺ Channel Modulator, Reveals Evidence for Functional Cooperation between Ca²⁺ Pumps and Ca²⁺ Release
Mol Pharmacol 2006 69: 1733-1739. Published online February 15, 2006; 10.1124/mol.105.020339 [Abstract] [Full Text] [PDF]  

Claudia Zierold, Jamie A. Mings, and Hector F. Deluca

19nor-1,25-Dihydroxyvitamin D₂ Specifically Induces CYP3A9 in Rat Intestine More Strongly than 1,25-Dihydroxyvitamin D₃ in Vivo and in Vitro
Mol Pharmacol 2006 69: 1740-1747. Published online February 16, 2006; 10.1124/mol.105.019851 [Abstract] [Full Text] [PDF]  

Xinjian Lin, Tsuyoshi Okuda, Julie Trang, and Stephen B. Howell

Human REV1 Modulates the Cytotoxicity and Mutagenicity of Cisplatin in Human Ovarian Carcinoma Cells
Mol Pharmacol 2006 69: 1748-1754. Published online February 22, 2006; 10.1124/mol.105.020446 [Abstract] [Full Text] [PDF]  

Antoine Roch, Vadim Shlyonsky, Arnaud Goolaerts, Frédérique Mies, and Sarah Sariban-Sohraby

Halothane Directly Modifies Na⁺ and K⁺ Channel Activities in Cultured Human Alveolar Epithelial Cells
Mol Pharmacol 2006 69: 1755-1762. Published online January 6, 2006; 10.1124/mol.105.021485 [Abstract] [Full Text] [PDF]  

Chau H. Nguyen and Val J. Watts

Dexamethasone-Induced Ras Protein 1 Negatively Regulates Protein Kinase C : Implications for Adenylyl Cyclase 2 Signaling
Mol Pharmacol 2006 69: 1763-1771. Published online February 17, 2006; 10.1124/mol.105.019133 [Abstract] [Full Text] [PDF]  

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